The Ultimate Muscle Peptide

RAMPS™ (Dileucine peptide) has multiple patents filed as a unique dipeptide for muscle health that has surpassed the gold standard of muscle protein synthesis (MPS) for the past 100 years, the amino acid leucine. The dileucine peptide uses special transporter in the gut for faster and more efficient absorption compared to individual amino acids. Ingestion of RAMPS™ does not only significantly increase free leucine plasma levels, it delivers intact dileucine as well.

Plasma dileucine concentrations after ingestion of 2g of leucine or 2g of dileucine (RAMPS™) in healthy young men. *Significant (p < 0.05) difference between conditions. Source: Kevin J.M. Paulussen et al. Dileucine ingestion is more effective than leucine in stimulating muscle protein turnover in young males: a double blind randomized controlled trial. J Appl Physiol 2021, 131:1111–1122.

Fast, Faster, Dileucine… after just 30 minutes, the dileucine peptide delivered 90% more leucine into the muscle (intramuscular) compared to ingesting the same amount of leucine (increase in intramuscular leucine levels after leucine or dileucine ingestion after 30 minutes: dileucine +345 ng/mL, leucine +182 ng/mL)!

Without exercise, ingestion of RAMPS™ significantly increased muscle protein synthesis by 60% over the previous best-in-class leucine in young health men!

Dileucine (RAMPS™) ingestion increase mean myofibrillar fractional synthetic rate by 60% compared to leucine in healthy young men. *Significant (p < 0.05) difference from rest. #Significant (p < 0.05) difference between conditions. Source: Kevin J.M. Paulussen et al. Dileucine ingestion is more effective than leucine in stimulating muscle protein turnover in young males: a double blind randomized controlled trial. J Appl Physiol 2021, 131:1111–1122.

RAMPS™ (Dileucine peptide) is revolutionizing muscle health with applications in sports nutrition, active nutrition, recovery, and for age related muscle loss. Dileucine occurs naturally as a component of plant and animal proteins, and is now available in its pure form.

The Benefits of RAMPS™

60% greater activation of mean muscle protein synthesis compared to leucine.
Significant increase in muscle protein synthesis without exercise.
Fast and efficient absorption into the muscle: 90% more leucine just 30 minutes after consumption
Intact dileucine peptide in plasma may augment the anabolic effects further

How does RAMPS™ Work?

Total muscle mass is always in flux with new muscle being built while at the same time parts of the muscle breaks down. Total muscle mass is the sum of muscle protein synthesis (MPS) and breakdown (MPB), and if synthesis is greater than breakdown, we are gaining muscle mass. The branched chain amino acid (BCAA) leucine is a key driver in the nutritional stimulation muscle protein synthesis. In order to optimally stimulate MPS, leucine levels have to reach a certain threshold amount. ING2 explored the kinetics of leucine and various leucine peptides and found that the dileucine peptide (L-leucyl-L-leucine) was much faster and more efficiently absorbed than standard leucine. This led to the discovery that faster absorption of leucine into the muscle provides greater activation of MPS. The fact that dileucine is at least in part absorbed intact might further augment its superior muscle building effects. RAMPS™ is a patented dileucine peptide that has been shown to be significantly more effective than leucine in inceasing MPS.